Showing posts with label Liver Cancer. Show all posts
Showing posts with label Liver Cancer. Show all posts

Tuesday, April 26, 2011

Energy saving bulbs can cause cancer

Updated on : Tuesday, April 26, 2011

BERLIN: Energy saving bulbs may help cut down electricity bill, but it can take a toll on health.
Fears have been reignited about the safety of energy saving light bulbs after a group of scientists warned that they contain cancer-causing chemicals. Their study has found that these energy saving bulbs emit cancer-causing chemicals when switched on.

Scientists in Germany have claimed that energy saving bulbs should not be left on for long periods of time or placed close to a person's head because they release poisonous materials.

The German study has shown that the chemicals are released as a form of steam. Scientists claimed that several carcinogenic chemicals and toxins were released when the environmentally-friendly compact fluorescent lamps (CFLs) were switched on, including phenol, naphthalene and styrene.

Friday, May 21, 2010

Sex hormone explains higher liver cancer risk in men

Updated on : Friday, May 21, 2010

HONG KONG: Male sex hormones may explain why men who suffer from the hepatitis B liver disease are more likely to develop liver cancer than women, researchers in Taiwan have found.

In a paper published in Science Translational Medicine, the researchers said hepatitis B viruses attach themselves to receptors of the male sex hormone androgen before going on to damage liver tissue and cause cancer.

"The findings indicate that using drugs to destroy ... androgen receptors could be a new way to battle liver cancer at an early stage," they wrote.

Liver cancer is the fifth most common cancer and the third leading cause of global cancer death.

Hepatitis B virus infection, which is endemic in many Asian countries including China, is a leading cause of liver cancer and accounts for half of liver cancer cases worldwide.

Men are up to seven times more likely than women to develop liver cancer. Among hepatitis B virus carriers, men are up to three times more likely to develop liver cancer than women.

Led by Ming-Heng Wu at the Institute of Basic Medical Sciences in National Cheng Kung University in Tainan, Taiwan, researchers found that hepatitis B viruses have a special DNA sequence which draws it to androgen receptors.

"The androgen receptors in liver cells bind to this sequence and trigger a cascade of damage to liver tissue," they explained.

In their experiment, the researchers created mice that were infected with the hepatitis B virus and could easily develop liver tumors upon exposure to cancer-causing agents.

Some of these were genetically modified to be lacking in androgen receptors in their livers.

By week 22 in the experiment, more than 90 percent of those mice with androgen receptors had developed liver tumors compared to 27 percent of the mice without androgen receptors.

Tinkering with the receptors did not change overall androgen levels or leave any obvious toxic effects in the mice.

"Targeting the androgen receptor rather an androgen could be a promising therapy for liver cancer," the researchers said.
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